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I am not computer expert but have had to use them from late 60's for fourier transform NMR. I was a research chemist (retired now for 27 years). We were encouraged to learn Fortran. which i never did. Few years later at the Unjv where I was a professor took week course in machine language.

I learned Fortran IV one summer during medical school (1967).
Did some trivially simple programming using a paper-tape feed for a Varian computer when spending a summer at NASA (1969).
Got a Radio Shack TRS-80 Model III (1979).