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Ground loops could be a problem if you connect the chassis to mains ground, and then plug into an amplifier that also has a mains ground. If the internal power supply is designed to be used as a double insulated appliance, then a safety ground to chassis isn't strictly necessary. If you do connect the keyboard chassis to ground, then am isolating DI box with "ground lift" may be needed in the audio line between the keyboard and any external amplifier.

The only other concern would be finding a suitable space inside the keyboard for the power supply, in my experience, internal space is at a premium in many keyboards. Have several trials to make sure everything fits in the available space with suitable clearance before doing anything irreversible like cutting a hole for the IEC connector. Also be aware that switched mode power supplies radiate electromagnetic noise, try to keep the power supply as far away as possible from sensitive audio circuits. If noise pick up is a problem, you may need to enclose the power supply in a metal box, (with suitable ventilation holes), connected to chassis ground.