Be aware that the compiler is built using programming Interfaces from recent versions of VM/370 under Hercules. That may disallow the use of CMS features which came along later (for example, the extended CMS file system that allows files with more than 64k records).
The modernized CMS runtime for BREXX has updated versions of the GCS runtime code on the GCCCMS user ID. The newer runtime is on the MAINTC ID within a disk search order setup using the GCCSRCH exec on that user ID.
Bob Bolch