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Re: Curcumin, turmeric and other cox 2 inhibitors


Wilhelm Hansen
 

Paul,
I am aware of what Mike Martin wrote and I responded to him after he wrote it (msg# 17578). What I found interesting in what you wrote and what I was asking about was specifically this paragraph...

Studies have reported that the enzymes used in these pathways were found to prefer the omega-3 pathway. It turns out then that in diets high in omega-3 fatty acids, most of the enzymes will be "busy" converting the omega-3 acids. <
...which led you to conclude the following:

So if I am deciphering this correctly, omega 3 pathway is naturally an inhibitor of arachidonic acid and if we inhibit the enzyme that inhibits 5 lo/cox 2, we also inhibit the conversion of omega 3s. It looks like we would need to do one or the other. Since the Budwig diet already "forbids" beef, lamb and pork (the major contributors of non-converted by the body) arachidonic acid, and the body also prefers omega 3 pathway over the omega 6, then it would seem that the Budwig Diet is all that is needed and one more reason the diet works. It also seems that the only supplement she (Budwig) wanted is yeast flakes which provides B vitamins.
More research needs to be done to determine if curcumin inhibits arachidonic acid conversion to 5 hete without the inhibition of omega 3 pathway. If so I would like to know so that I may add it back into my supplement plan. I do not think it wise to take anything that will inhibit the omega 3 pathway and therefore inhibit the Budwig diet. <
Wilhelm




Wilhelm,
The references to the cox inhibitors is in message I posted #20986.
This was taken from a post by the authors of www.flaxrd.com .
I am hoping that the action of 5 lo inhibitors is after the main
conversions of omega 3 and that the specific cox 2 inhibition does
not effect the conversion of omega 3. I don't know and I would like
to know an answer.
Paul

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